Clinical Overview Patient Handouts Trainings and PowerPoint Presentations Additional Resources Clinical Overview The concept of a viral hemorrhagic fever (VHF) syndrome is useful in clinical medicine. VHF syndrome can be described as an acute febrile illness characterized by malaise, prostration, generalized signs of increased vascular permeability and abnormalities of circulatory regulation. The viral agents that […]
Bioterrorism
Tularemia
Clinical Overview Patient Handouts Trainings and PowerPoint Presentations Additional Resources Clinical Overview Tularemia is a zoonosis caused by the Gram negative, facultative intracellular bacterium, nonmotile, obligately aerobic Francisella tularensis. In 1911, G. W. McCoy discovered the disease in Tulare County, California as a cause of a plague-like illness in ground squirrels. Edward Francis subsequently described transmission […]
Smallpox
Clinical Overview Patient Handouts Trainings and PowerPoint Presentations Additional Resources Clinical Overview The poxviruses (of the family Poxviridae) are a family of large, enveloped deoxyribonucleic acid (DNA) viruses. The most notorious poxvirus is variola, the causative agent of smallpox. Smallpox was an important cause of morbidity and mortality until recent times. Since the host range of […]
Cyanide
Clinical Overview Patient Handouts Trainings and PowerPoint Presentations Additional Resources Clinical Overview Cyanide has been recognized since antiquity as a poison that is present in bitter almonds, cassava and other foods. The purified gaseous form, hydrogen cyanide [HCN], was discovered in the 18th century. Currently several forms are used extensively in industry for tasks such […]
Brucellosis
Clinical Overview Patient Handouts Trainings and PowerPoint Presentations Additional Resources Clinical Overview Brucellosis is an infectious disease caused by the bacteria of the genusBrucella often known as undulant fever. Brucella species are gram-negative cocco-bacillary organisms, of which four are pathogenic in humans (Brucella melitensis, B. abortus, B. canis and B. suis). They are highly infectious, especially B. melitensis and B. suis. Most human […]
Botulism
Clinical Overview Patient Handouts Trainings and PowerPoint Presentations Additional Resources Clinical Overview The clostridial neurotoxins are the most toxic substances known to science. The neurotoxins produced from Clostridium tetani (tetanus toxin) and Clostridium botulinum (ie, the botulinum toxins, of which there are seven in all), are the most likely to be contacted by humans. The primary means of […]
Anthrax
Clinical Overview Patient Handouts Trainings and PowerPoint Presentations Additional Resources Clinical Overview Anthrax, is a zoonotic disease caused by Bacillus anthracis. It occurs in domesticated and wild animals, primarily herbivores, including goats, sheep, cattle, horses and swine. Humans usually become infected by contact with infected animals or contaminated animal products. Infection occurs most commonly via […]